Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

ver descrição completa

Detalhes bibliográficos
Autor principal: Beevers, J
Outros Autores: Wade-Martins, R
Formato: Thesis
Idioma:English
Publicado em: 2016
Assuntos: