Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons
<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...
Autor Principal: | Beevers, J |
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Outros autores: | Wade-Martins, R |
Formato: | Thesis |
Idioma: | English |
Publicado: |
2016
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Subjects: |
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