Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

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Detalles Bibliográficos
Autor Principal: Beevers, J
Outros autores: Wade-Martins, R
Formato: Thesis
Idioma:English
Publicado: 2016
Subjects:

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