Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

Investigating the function of microtubule-associated protein tau (MAPT) and its genetic association with Parkinson’s using human iPSC-derived dopamine neurons

<p>Parkinson's disease (PD) primarily manifests as loss of motor control through the degeneration of nigrostriatal dopaminergic neurons. The microtubule-associated protein tau (<em>MAPT</em>) locus is highly genetically associated with PD, wherein the H1 haplotype confers dise...

書目詳細資料
主要作者:	Beevers, J
其他作者:	Wade-Martins, R
格式:	Thesis
語言:	English
出版:	2016
主題:	Neurodegeneration Parkinson's disease Induced pluripotent stem cells

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