A THEORETICAL FRAMEWORK FOR SELF-TOLERANCE AND ITS RELEVANCE TO THERAPY OF AUTOIMMUNE-DISEASE

Therapeutic intervention in autoimmune diseases should be based on a knowledge of how the normal immune system maintains unresponsiveness to 'self' and how this state of unresponsiveness may be broken. We have proposed that 'self' from the viewpoint of T cells may represent only...

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Bibliographic Details
Main Authors: Waldmann, H, Cobbold, S, Benjamin, R, Qin, S
Format: Journal article
Language:English
Published: 1988