Positional cloning of a novel gene influencing asthma from chromosome 2q14.

Asthma is a common disease in children and young adults. Four separate reports have linked asthma and related phenotypes to an ill-defined interval between 2q14 and 2q32 (refs. 1-4), and two mouse genome screens have linked bronchial hyper-responsiveness to the region homologous to 2q14 (refs. 5,6)....

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Main Authors: Allen, M, Heinzmann, A, Noguchi, E, Abecasis, G, Broxholme, J, Ponting, C, Bhattacharyya, S, Tinsley, J, Zhang, Y, Holt, R, Jones, E, Lench, N, Carey, A, Jones, H, Dickens, N, Dimon, C, Nicholls, R, Baker, C, Xue, L, Townsend, E, Kabesch, M, Weiland, S, Carr, D, von Mutius, E, Adcock, I
Format: Journal article
Language:English
Published: 2003