Neuropathologic evidence of endothelial changes in cerebral small vessel disease.

OBJECTIVES: Cerebral small vessel disease (SVD) is common in aged brains and causes lacunar stroke, diffuse white matter lesions (leukoaraiosis), and vascular cognitive impairment. The pathogenesis is unknown. Endothelial dysfunction is a possible causal factor, and circulating markers of endothelia...

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Bibliographic Details
Main Authors: Giwa, M, Williams, J, Elderfield, K, Jiwa, N, Bridges, L, Kalaria, R, Markus, H, Esiri, M, Hainsworth, A
Format: Journal article
Language:English
Published: 2012