Reaching the end-game for GWAS: Machine learning approaches for the prioritization of complex disease loci

Genome-wide association studies (GWAS) have revealed thousands of genetic loci that underpin the complex biology of many human traits. However, the strength of GWAS – the ability to detect genetic association by linkage disequilibrium (LD) – is also its limitation. Whilst the ever-increasing study s...

詳細記述

書誌詳細
主要な著者: Nicholls, HL, John, CR, Watson, DS, Munroe, PB, Barnes, MR, Cabrera, CP
フォーマット: Journal article
言語:English
出版事項: Frontiers 2020