Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.

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Hepatitis C virus (HCV)-specific CD8(+) T cells in persistent HCV infection are low in frequency and paradoxically show a phenotype associated with controlled infections, expressing the memory marker CD127. We addressed to what extent this phenotype is dependent on the presence of cognate antigen. W...

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Bibliographic Details
Main Authors: Kasprowicz, V, Kang, Y, Lucas, M, Schulze zur Wiesch, J, Kuntzen, T, Fleming, V, Nolan, B, Longworth, S, Berical, A, Bengsch, B, Thimme, R, Lewis-Ximenez, L, Allen, T, Kim, A, Klenerman, P, Lauer, G
Format: Journal article
Language:English
Published: 2010

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