Heterobiaryl synthesis by contractive C-C coupling via P(V) intermediates

Heterobiaryls composed of pyridine and diazine rings are key components of pharmaceuticals and are often central to pharmacological function. We present an alternative approach to metal-catalyzed cross-coupling to make heterobiaryls using contractive phosphorus C–C couplings, also termed phosphorus...

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Bibliographic Details
Main Authors: Hilton, M, Zhang, X, Boyle, B, Alegre-Requena, J, Paton, R, McNally, A
Format: Journal article
Language:English
Published: American Association for the Advancement of Science 2018