The role of novel genetic and epigenetic mechanisms in the development of type 2 diabetes
<p>Type 2 diabetes (T2D) is a metabolic disease characterised by insulin resistance and beta-cell failure and a leading cause of mortality and morbidity. GWAS have identified pancreatic beta-cell dysfunction as a major player in T2D pathogenesis, but since the majority of signals reside in non...
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Format: | Thesis |
Language: | English |
Published: |
2016
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