The role of novel genetic and epigenetic mechanisms in the development of type 2 diabetes

<p>Type 2 diabetes (T2D) is a metabolic disease characterised by insulin resistance and beta-cell failure and a leading cause of mortality and morbidity. GWAS have identified pancreatic beta-cell dysfunction as a major player in T2D pathogenesis, but since the majority of signals reside in non...

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Bibliographic Details
Main Author: Thurner, M
Other Authors: McCarthy, M
Format: Thesis
Language:English
Published: 2016
Subjects:

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