Nonopsonic phagocytosis of Pseudomonas aeruginoas: insights from an infant with leukocyte adhesion deficiency.

Children with leukocyte adhesion deficiency type I are at risk for overwhelming infection because their neutrophils lack surface beta 2 integrins (CD18/CD11) that normally interact with endothelial cell adhesion molecules and mediate migration to sites of bacterial invasion. In vitro studies of phag...

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Bibliographic Details
Main Authors: Pollard, A, Heale, J, Tsang, A, Massing, B, Speert, D
Format: Journal article
Language:English
Published: 2001