Nonopsonic phagocytosis of Pseudomonas aeruginoas: insights from an infant with leukocyte adhesion deficiency.
Children with leukocyte adhesion deficiency type I are at risk for overwhelming infection because their neutrophils lack surface beta 2 integrins (CD18/CD11) that normally interact with endothelial cell adhesion molecules and mediate migration to sites of bacterial invasion. In vitro studies of phag...
Main Authors: | Pollard, A, Heale, J, Tsang, A, Massing, B, Speert, D |
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Format: | Journal article |
Language: | English |
Published: |
2001
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