Heterogeneity in Ewing sarcoma

Heterogeneity in Ewing sarcoma

<p>Ewing sarcoma, an aggressive primary bone and soft tissue tumour is characterised by the expression of the chimeric transcription factor EWS-FLI1 in 90% of patients. This alters expression of many genes including activation of the Insulin Growth Factor (IGF) pathway via IGFBP3 supression. P...

Полное описание

Библиографические подробности
Главный автор:	Branford White, HA
Другие авторы:	Hassan, A
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Pathology Orthopaedics Oncology

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