Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
The PIM family of serine/threonine kinases have become an attractive target for anti-cancer drug development, particularly for certain hematological malignancies. Here, we describe the discovery of a series of inhibitors of the PIM kinase family using a high throughput screening strategy. Through a...
| Hauptverfasser: | , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
Elsevier
2017
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