Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.

The PIM family of serine/threonine kinases have become an attractive target for anti-cancer drug development, particularly for certain hematological malignancies. Here, we describe the discovery of a series of inhibitors of the PIM kinase family using a high throughput screening strategy. Through a...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Bataille, C, Brennan, M, Byrne, S, Davies, S, Durbin, M, Fedorov, O, Huber, K, Jones, A, Knapp, S, Liu, G, Nadali, A, Quevedo, C, Russell, A, Walker, R, Westwood, R, Wynne, G
التنسيق: Journal article
اللغة:English
منشور في: Elsevier 2017

مواد مشابهة

مواد مشابهة