Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology

Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology

<p><strong>Background:</strong>&nbsp;Duchenne muscular dystrophy (DMD) is a fatal muscle‐wasting disorder caused by genetic loss of dystrophin protein. Extracellular microRNAs (ex‐miRNAs) are putative, minimally invasive biomarkers of DMD. Specific ex‐miRNAs (e.g. miR‐1, miR‐13...

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Bibliographic Details
Main Authors: Van Westering, T, Lomonosova, Y, Coenen‐Stass, A, Betts, C, Bhomra, A, Hulsker, M, Clark, L, McClorey, G, Aartsma‐Rus, A, Putten, M, Wood, M, Roberts, T
Format: Journal article
Language:English
Published: Wiley 2019

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