Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.

Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.

BACKGROUND: Prostaglandin D2 (PGD2) and cysteinyl leukotrienes (cysLTs) are lipid mediators derived from mast cells, which activate TH2 cells. The combination of PGD2 and cysLTs (notably cysteinyl leukotriene E4 [LTE4]) enhances TH2 cytokine production. However, the synergistic interaction of cysLTs...

書誌詳細
主要な著者:	Xue, L, Fergusson, J, Salimi, M, Panse, I, Ussher, J, Hegazy, A, Vinall, S, Jackson, D, Hunter, MG, Pettipher, R, Ogg, G, Klenerman, P
フォーマット:	Journal article
言語:	English
出版事項:	Elsevier 2015

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