Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are synthesized from Glc3Man9GlcNAc2 precursors that are trimmed and modified in the endoplasmic reticulum (ER) and Golgi apparatus by glycoside hy...
Κύριοι συγγραφείς: | Sobala, Ł, Fernandes, PZ, Hakki, Z, Thompson, AJ, Howe, JD, Hill, M, Zitzmann, N, Davies, S, Stamataki, Z, Butters, TD, Alonzi, DS, Williams, SJ, Davies, GJ |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
National Academy of Sciences
2020
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase.
ανά: Thompson, A, κ.ά.
Έκδοση: (2012) -
Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.
ανά: Butters, T, κ.ά.
Έκδοση: (2009) -
Therapeutic targets for inhibitors of glycosylation.
ανά: Alonzi, D, κ.ά.
Έκδοση: (2011) -
Norman Manea dialogue avec Hélène Lenz
ανά: Norman Manea, κ.ά.
Έκδοση: (2013-12-01) -
DISCOVERY OF A SELECTIVE LYSOSOMAL ALPHA-MANNOSIDASE INHIBITOR FROM AN IMINO-SUGAR LIBRARY
ανά: Chang, Y, κ.ά.
Έκδοση: (2014)