Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma
The intra-tumour microenvironment generates phenotypically distinct but inter-convertible malignant cell subpopulations that fuel metastatic spread and therapeutic-resistance. Whether different microenvironmental cues impose invasive or therapy-resistant phenotypes via a common mechanism is unknown....
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Cold Spring Harbor Laboratory Press
2017
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