Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma

Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma

The intra-tumour microenvironment generates phenotypically distinct but inter-convertible malignant cell subpopulations that fuel metastatic spread and therapeutic-resistance. Whether different microenvironmental cues impose invasive or therapy-resistant phenotypes via a common mechanism is unknown....

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Bibliographic Details
Main Authors:	Falletta, P, Sanchez-del-Campo, L, Chauhan, J, Effern, M, Kenyon, A, Kershaw, C, Siddaway, R, Lisle, R, Freter, R, Daniels, M, Lu, X, Tüting, T, Middleton, M, Buffa, F, Willis, A, Pavitt, G, Ronai, Z, Sauka-Spengler, T, Hölzel, M, Goding, C
Format:	Journal article
Published:	Cold Spring Harbor Laboratory Press 2017

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