Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding

<p style="text-align:justify;"> <b>Background:</b> The mouse has three arylamine N-acetyltransferase genes, (MOUSE)Nat1, (MOUSE)Nat2 and (MOUSE)Nat3. These are believed to correspond to (HUMAN)NAT1, (HUMAN)NAT2 and NATP in humans. (MOUSE)Nat3 encodes an enzyme with poor...

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Detalhes bibliográficos
Principais autores: Laurieri, N, Kawamura, A, Westwood, I, Varney, A, Morris, E, Russell, A, Stanley, L, Sim, E
Formato: Journal article
Idioma:English
Publicado em: BioMed Central 2014