Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR.

Interferon stimulates the expression of a number of genes encoding enzymes with antiviral activities, including myxovirus resistance-1 (MxA), 2-5-oligoadenylate synthetase 1 (OAS-1) and double-stranded RNA-dependent protein kinase (PKR). We examined whether polymorphisms in these genes influenced th...

Full description

Bibliographic Details
Main Authors:	Knapp, S, Yee, L, Frodsham, A, Hennig, B, Hellier, S, Zhang, L, Wright, M, Chiaramonte, M, Graves, M, Thomas, H, Hill, A, Thursz, MR
Format:	Journal article
Language:	English
Published:	2003

Polymorphisms in interferon-induced genes and the outcome of hepatitis C virus infection: roles of MxA, OAS-1 and PKR.

Similar Items