Fragment-based identification of ligands for bromodomain-containing factor 3 of Trypanosoma cruzi

The Trypanosoma cruzi (T. cruzi) parasite is the cause of Chagas disease, a neglected disease endemic in South America. The life cycle of the T. cruzi parasite is complex and includes transitions between distinct life stages. This change in phenotype (without a change in genotype) could be controlle...

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Bibliographic Details
Main Authors: Laurin, CMC, Bluck, JP, Chan, AKN, Keller, M, Boczek, A, Scorah, AR, See, KFL, Jennings, LE, Hewings, DS, Woodhouse, F, Reynolds, JK, Schiedel, M, Humphreys, PG, Biggin, PC, Conway, SJ
Format: Journal article
Language:English
Published: American Chemical Society 2020