DNA fusion vaccines incorporating IL-23 or RANTES for use in immunization against influenza.

The incorporation of RANTES or IL-23 into DNA vaccines may improve their immunogenicity by the recruitment and activation of dendritic cells. This may also select for a TH1 response counteracting the TH2 response which can predominate when a DNA vaccine is delivered by gene gun. We have immunized mi...

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Bibliographic Details
Main Authors: Williman, J, Young, S, Buchan, G, Slobbe, L, Wilson, M, Pang, P, Austyn, J, Preston, S, Baird, M
Format: Journal article
Language:English
Published: 2008