Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.

BACKGROUND: Homocystinemia is a metabolic abnormality associated with endothelial dysfunction and increased cardiovascular disease risk. The underlying mechanisms of these effects, however, are obscure. OBJECTIVE: We examined the effect of asymmetrical dimethylarginine (ADMA) on endothelial dysfunc...

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Bibliographic Details
Main Authors: Antoniades, C, Tousoulis, D, Marinou, K, Vasiliadou, C, Tentolouris, C, Bouras, G, Pitsavos, C, Stefanadis, C
Format: Journal article
Language:English
Published: 2006