Revisiting the effect of acute P. falciparum malaria on Epstein-Barr virus: host balance in the setting of reduced malaria endemicity.

Burkitt's lymphoma (BL), an EBV-associated tumour, occurs at high incidence in populations where malaria is holoendemic. Previous studies in one such population suggested that acute P.falciparum infection impairs EBV-specific T-cell surveillance, allowing expansion of EBV infected B-cells from...

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Bibliographic Details
Main Authors: Jayasooriya, S, Hislop, A, Peng, Y, Croom-Carter, D, Jankey, Y, Bell, A, Dong, T, Rowland-Jones, S, Rickinson, A, Walther, M, Whittle, H
Format: Journal article
Language:English
Published: Public Library of Science 2012