RNA splicing: disease and therapy.
The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. The mechanism of pre-mRNA splicing is highly complex, requiring multiple interactions between pre-mRNA, small nuclear ribonucleoprotei...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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