Signaling pathways activated by a protease allergen in basophils

Allergic diseases represent a significant burden in industrialized countries, but why and how the immune system responds to allergens remain largely unknown. Because many clinically significant allergens have proteolytic activity, and many helminths express proteases that are necessary for their lif...

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Bibliographic Details
Main Authors: Rosenstein, R, Bezbradica, J, Yu, S, Medzhitov, R
Format: Journal article
Language:English
Published: National Academy of Sciences 2014