Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress.

Mammalian ALDH7A1 is homologous to plant ALDH7B1, an enzyme that protects against various forms of stress, such as salinity, dehydration, and osmotic stress. It is known that mutations in the human ALDH7A1 gene cause pyridoxine-dependent and folic acid-responsive seizures. Herein, we show for the fi...

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Bibliographic Details
Main Authors: Brocker, C, Lassen, N, Estey, T, Pappa, A, Cantore, M, Orlova, V, Chavakis, T, Kavanagh, K, Oppermann, U, Vasiliou, V
Format: Journal article
Language:English
Published: 2010