Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.

Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.

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PURPOSE: The expression of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) is associated with poor prognosis in sporadic colorectal carcinoma (CRC). EGFR inhibitors are approved for the treatment of refractory CRC. The aim of this study was to investigate...

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Библиографические подробности
Главные авторы:	Wang, J, Hollingshead, J, El-Masry, N, Horncastle, D, Talbot, I, Tomlinson, I, Alison, MR, El-Bahrawy, M
Формат:	Journal article
Язык:	English
Опубликовано:	2012

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