Expression of EGFR, HER2, phosphorylated ERK and phosphorylated MEK in colonic neoplasms of familial adenomatous polyposis patients.
PURPOSE: The expression of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) is associated with poor prognosis in sporadic colorectal carcinoma (CRC). EGFR inhibitors are approved for the treatment of refractory CRC. The aim of this study was to investigate...
Main Authors: | Wang, J, Hollingshead, J, El-Masry, N, Horncastle, D, Talbot, I, Tomlinson, I, Alison, MR, El-Bahrawy, M |
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格式: | Journal article |
语言: | English |
出版: |
2012
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