Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins

Design, implementation and experimental validation of a network-based model to predict mitotic microtubule regulating proteins

<p>The purpose of this thesis was to study mitosis in Drosophila, from a network biology perspective. The primary aim was to develop and test a network-based prediction model that could integrate available data in public databases (like Flybase) and, based on that, predict potential mitotic pr...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur:	Khan, FF
Awduron Eraill:	Deane, C
Fformat:	Traethawd Ymchwil
Iaith:	English
Cyhoeddwyd:	2013
Pynciau:	Cell Biology (see also Plant sciences) Bioinformatics (life sciences) Biology

Eitemau Tebyg

Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly
gan: Duncan, T
Cyhoeddwyd: (2011)

The evolution of eukaryotic cilia
gan: Hodges, M, et al.
Cyhoeddwyd: (2011)

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis
gan: Meireles, A, et al.
Cyhoeddwyd: (2009)

The role and regulation of Asterless in the centrosome cycle
gan: Novak, ZA
Cyhoeddwyd: (2014)

Regulation and reproductive functions of membrane-bound vesicles secreted by the Drosophila male accessory gland
gan: Corrigan, L
Cyhoeddwyd: (2014)

Functions of conserved centriole proteins in African trypanosomes
gan: Scheumann, N
Cyhoeddwyd: (2012)

Characterisation of AEBP2: a polycomb repressive complex 2 component
gan: Grijzenhout, A
Cyhoeddwyd: (2013)

Functional organisation of the Hrd1 ubiquitin ligase complex and its role in ERAD
gan: Schulz, J
Cyhoeddwyd: (2013)

The role of Adaptor Protein 3 in cytotoxic T lymphocytes
gan: Wenham, M
Cyhoeddwyd: (2009)

The role of protein kinase C in platelet activation
gan: Unsworth, AJ
Cyhoeddwyd: (2012)

Cell stress response and hypoxia in breast cancer
gan: Milani, M, et al.
Cyhoeddwyd: (2011)

Nitric oxide: a chemical effector of pathogenesis in magnaporthe oryzae
gan: Johnson, J
Cyhoeddwyd: (2011)

Automated segmentation and alignment of mitotic nuclei for Kymograph visualisation
gan: Li, S, et al.
Cyhoeddwyd: (2011)

Deconstructing the trypanosome cytoskeleton: from structures to functions via components and complexes.
gan: Portman, N
Cyhoeddwyd: (2011)

Towards understanding the mechanism of cohesin loading
gan: Dixon, SE
Cyhoeddwyd: (2013)

Assessing the role of ADAM10 in Trastuzumab treatment and resistance
gan: Feldinger, K
Cyhoeddwyd: (2012)

Syncrip regulates mRNA localisation and translation at the drosophila neuromuscular junction
gan: Halstead, J
Cyhoeddwyd: (2013)

Factors contributing to chondroplasia in degenerate rotator cuff disease
gan: Cornell, HR
Cyhoeddwyd: (2011)

The automated analysis and statistical characterisation of subcellular biological images
gan: Li, S, et al.
Cyhoeddwyd: (2012)

Effect of CTCF and Cohesin on the dynamics of RNA polymerase II transcription and coupled pre-messenger RNA processing
gan: Liska, O
Cyhoeddwyd: (2013)

Investigation into the mechanisms of cytoophidia assembly in drosophila melanogaster
gan: Aughey, GN
Cyhoeddwyd: (2014)

Identification and characterisation of homologous recombination genes in Schizosaccharomyces pombe
gan: Moss, J
Cyhoeddwyd: (2011)

Segmentation of cell clumps for quantitative analysis
gan: Li, S
Cyhoeddwyd: (2010)

Structure-function studies of fibronectin domains in the human endometrium
gan: Mok, M, et al.
Cyhoeddwyd: (2008)

Elucidating the pathway of centrosome formation
gan: Costa Vicente, C
Cyhoeddwyd: (2013)

Regulation of E2F-1 by methylation and NEDDylation
gan: Loftus, S, et al.
Cyhoeddwyd: (2012)

The relation between multilocus population genetics and social evolution theory
gan: Gardner, A, et al.
Cyhoeddwyd: (2007)

Induced regulatory T cells in transplantation tolerance
gan: Chen, Y
Cyhoeddwyd: (2010)

Investigating the effects of a point mutation in the TRPC3 channel – cause of cerebellar ataxia in Moonwalker mice – on the Purkinje cells in mice
gan: Dulneva, A
Cyhoeddwyd: (2012)

Protein loop structure prediction
gan: Choi, Y
Cyhoeddwyd: (2011)

Determining the mechanism of pathogenesis of mucolipidosis type IV and related lysosomal storage disorders for development of novel therapies
gan: Peterneva, K
Cyhoeddwyd: (2014)

Expression of two-pore channels in mammalian primary cells and tissues, and their role in adipose tissue formation and function
gan: Tunn, R
Cyhoeddwyd: (2012)

Analysis of artificial chromosomes in human embryonic stem cells
gan: Mandegar, M
Cyhoeddwyd: (2011)

Human orthologues of Saccharomyces cerevisiae Trf4/5 non-canonical poly(A) polymerases
gan: Gibson, K
Cyhoeddwyd: (2011)

A microtubule interactome: complexes with roles in cell cycle and mitosis
gan: Hughes, J, et al.
Cyhoeddwyd: (2008)

Evolutionary usage and developmental roles of vertebrate non-methylated DNA
gan: Long, HK
Cyhoeddwyd: (2014)

Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase
gan: Zayer, A
Cyhoeddwyd: (2012)

Mucosal associated invariant T cells and related CD161 expressing T lymphocytes
gan: Fergusson, J, et al.
Cyhoeddwyd: (2015)

Studies on HIF hydroxylases
gan: Webb, J
Cyhoeddwyd: (2008)

E2F7: a member of the E2F family with a novel mechanism of transcriptional repression
gan: Kesoglidou, PX
Cyhoeddwyd: (2012)