Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification

Stromal-derived intratumoural heterogeneity (ITH) has been shown to undermine molecular stratification of patients into appropriate prognostic/predictive subgroups. Here, using several clinically relevant colorectal cancer (CRC) gene expression signatures, we assessed the susceptibility of these sig...

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Bibliographic Details
Main Authors: Dunne, P, Alderdice, M, O'Reilly, P, Roddy, A, McCorry, A, Richman, S, Maughan, T, McDade, S, Johnston, P, Longley, D, Kay, E, McArt, D, Lawler, M
Format: Journal article
Language:English
Published: Springer Nature 2017

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