Manipulating regulatory T cells: is it the key to unlocking effective immunotherapy for pancreatic ductal adenocarcinoma?

The five-year survival rates for pancreatic ductal adenocarcinoma (PDAC) have scarcely improved over the last half-century. It is inherently resistant to FDA-approved immunotherapies, which have transformed the outlook for patients with other advanced solid tumours. Accumulating evidence relates thi...

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Bibliographic Details
Main Authors: Smith, H, Arbe-Barnes, E, Shah, EA, Sivakumar, S
Format: Journal article
Language:English
Published: Frontiers Media 2024