Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type 2 diabetes, cardiovascular disease and related metabolic and inflammatory disturbances. Although the mechanisms linking adiposity to associated clinical conditions are poorly understo...

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Main Authors: Wahl, S, Drong, A, Lehne, B, Loh, M, Scott, W, Kunze, S, Tsai, P, Ried, J, Zhang, W, Yang, Y, Tan, S, Fiorito, G, Franke, L, Guarrera, S, Kasela, S, Kriebel, J, Richmond, R, Adamo, M, Afzal, U, Ala-Korpela, M, Albetti, B, Ammerpohl, O, Apperley, J, Beekman, M, Bertazzi, P, Black, S, Blancher, C, Bonder, M, Brosch, M, Carstensen-Kirberg, M, de Craen, A, de Lusignan, S, Dehghan, A, Elkalaawy, M, Fischer, K, Franco, O, Gaunt, T, Hampe, J, Hashemi, M, Isaacs, A, Jenkinson, A, Jha, S, Kato, N, Krogh, V, Laffan, M, Meisinger, C, Meitinger, T, Mok, Z, Motta, V, Ng, H, Nikolakopoulou, Z, Nteliopoulos, G, Panico, S, Pervjakova, N, Prokisch, H, Rathmann, W, Roden, M, Rota, F, Rozario, M, Sandling, J, Schafmayer, C, Schramm, K, Siebert, R, Slagboom, P, Soininen, P, Stolk, L, Strauch, K, Tai, E, Tarantini, L, Thorand, B, Tigchelaar, E, Tumino, R, Uitterlinden, A, van Duijn, C, van Meurs, J, Vineis, P, Wickremasinghe, A, Wijmenga, C, Yang, T, Yuan, W, Zhernakova, A, Batterham, R, Smith, G, Deloukas, P, Heijmans, B, Herder, C, Hofman, A, Lindgren, C, Milani, L, van der Harst, P, Peters, A, Illig, T, Relton, C, Waldenberger, M, Järvelin, M, Bollati, V, Soong, R, Spector, T, Scott, J, McCarthy, M, Elliott, P, Bell, J, Matullo, G, Gieger, C, Kooner, J, Grallert, H, Chambers, J
Format: Journal article
Language:English
Published: Nature Publishing Group 2016