Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers.

Affymetrix U133plus2 GeneChips were used to profile 59 head and neck squamous cell cancers. A hypoxia metagene was obtained by analysis of genes whose in vivo expression clustered with the expression of 10 well-known hypoxia-regulated genes (e.g., CA9, GLUT1, and VEGF). To minimize random aggregatio...

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Bibliographic Details
Main Authors: Winter, S, Buffa, F, Silva, P, Miller, C, Valentine, H, Turley, H, Shah, K, Cox, G, Corbridge, R, Homer, J, Musgrove, B, Slevin, N, Sloan, P, Price, P, West, C, Harris, A
Format: Journal article
Language:English
Published: 2007