Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex

Inducible genes in yeast retain a "memory" of recent transcriptional activity during periods of short-term repression, allowing them to be reactivated faster when reinduced. This confers a rapid and versatile gene expression response to the environment. We demonstrate that this memory mech...

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Autori principali: Tan-Wong, S, Wijayatilake, H, Proudfoot, N
Natura: Journal article
Lingua:English
Pubblicazione: Cold Spring Harbor Laboratory Press 2009