Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Bibliographic Details
Main Authors: Salio, M, Puleston, D, Mathan, T, Shepherd, D, Stranks, A, Adamopoulou, E, Veerapen, N, Besra, G, Hollander, G, Simon, A, Cerundolo, V
Format: Journal article
Language:English
Published: National Academy of Sciences 2014