Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Detalhes bibliográficos
Main Authors: Salio, M, Puleston, D, Mathan, T, Shepherd, D, Stranks, A, Adamopoulou, E, Veerapen, N, Besra, G, Hollander, G, Simon, A, Cerundolo, V
Formato: Journal article
Idioma:English
Publicado em: National Academy of Sciences 2014