Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

<strong>Background</strong> Population suppression gene drive has been proposed as a strategy for malaria vector control. A CRISPR-Cas9-based transgene homing at the doublesex locus (dsxFCRISPRh) has recently been shown to increase rapidly in frequency in, and suppress, caged laboratory...

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Bibliographic Details
Main Authors: Connolly, JB, Mumford, JD, Fuchs, S, Turner, G, Beech, C, North, AR, Burt, A
Format: Journal article
Language:English
Published: BioMed Central 2021