The JAK inhibitor baricitinib inhibits oncostatin M induction of proinflammatory mediators in ex-vivo synovial derived cells

<p><strong>Objectives:</strong></p> To investigate the ex vivo effect of the JAK1/2 inhibitor baricitinib on expression of pro-inflammatory mediators in rheumatoid arthritis (RA) fibroblast like synoviocytes (FLS) stimulated with TNFα, IL-1β and oncostatin M (OSM), and in RA...

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Бібліографічні деталі
Автори: Weston, S, Macdonald, JL, Williams, LM, Roussou, E, Kang, NV, Kiriakidis, S, Taylor, PC
Формат: Journal article
Мова:English
Опубліковано: Pacini Editore SpA 2022