Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by dystrophin deficiency. In normal muscle, dystrophin helps maintain sarcolemmal stability. Dystrophin also recruits neuronal nitric oxide synthase (nNOS) to the sarcolemma. Failure to anchor nNOS to the membrane leads to functiona...
| Main Authors: | , , , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado: |
2010
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