Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension.

The locus encompassing the corticosteroidogenic genes CYP11B2 and CYP11B1 is of potential importance in essential hypertension. We analyzed the association of polymorphisms at this locus with risk of essential hypertension, using 2 white case-control collections for discovery (n=3340) and confirmati...

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Dades bibliogràfiques
Autors principals: Alvarez-Madrazo, S, Mackenzie, S, Davies, E, Fraser, R, Lee, W, Brown, M, Caulfield, M, Dominiczak, A, Farrall, M, Lathrop, M, Hedner, T, Melander, O, Munroe, P, Samani, N, Stewart, P, Wahlstrand, B, Webster, J, Palmer, C, Padmanabhan, S, Connell, J
Format: Journal article
Idioma:English
Publicat: 2013