A noninvasive comparison study between human gliomas with IDH1 and IDH2 mutations by MR spectroscopy

<p>The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acids, and fatty acid metabolism. Mutations in isocitrate dehydrogenase genes (IDH1/2) in diffuse gliomas are associated with abnormally high levels of 2-hydroxyglutarate (2-HG) levels. The aim of th...

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מידע ביבליוגרפי
Main Authors: Shen, X, Voets, N, Larkin, S, De Pennington, N, Plaha, P, Stacey, R, McCullagh, J, Schofield, C, Clare, S, Jezzard, P, Cadoux-Hudson, T, Ansorge, O, Emir, U
פורמט: Journal article
שפה:English
יצא לאור: MDPI 2019