Repopulating microglia promote brain repair in an IL-6-dependent manner
Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and secondary inflammatory pathology remains poorly understood. Here, we show that removal of microglia from the mouse brain has little effect on the o...
المؤلفون الرئيسيون: | Willis, EF, MacDonald, KPA, Nguyen, QH, Garrido, AL, Gillespie, ER, Harley, SBR, Bartlett, PF, Schroder, WA, Yates, AG, Anthony, DC, Rose-John, S, Ruitenberg, MJ, Vukovic, J |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Cell Press
2020
|
مواد مشابهة
-
Exercise rejuvenates microglia and reverses T cell accumulation in the aged female mouse brain
حسب: Chauquet, S, وآخرون
منشور في: (2024) -
Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury
حسب: Yates, AG, وآخرون
منشور في: (2021) -
Tracking changes in functionality and morphology of repopulated microglia in young and old mice
حسب: Zuzanna M. Luczak-Sobotkowska, وآخرون
منشور في: (2024-10-01) -
Systemic immune response to traumatic CNS injuries—are extracellular vesicles the missing link?
حسب: Yates, AG, وآخرون
منشور في: (2019) -
Microglia depletion/repopulation does not affect light-induced retinal degeneration in mice
حسب: Nils Laudenberg, وآخرون
منشور في: (2024-01-01)