Unnatural co-substrate-based rescue of enzyme activity in Refsum's disease resulting from mutations in R275 of phytanoyl-CoA hydroxylase.
Príomhchruthaitheoirí: | Lloyd, MD, Mukherji, M, Kershaw, N, MacKinnon, C, Schofield, C, Wierzbicki, A |
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Formáid: | Journal article |
Foilsithe / Cruthaithe: |
2000
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Míreanna comhchosúla
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'Chemical co-substrate rescue' of phytanoyl-CoA 2-hydroxylase mutants causing Refsum's Disease
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Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease.
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Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.
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Role of phytanoyl-CoA 2-hydroxylase in phytanic acid metabolism.
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Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.
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