NAADP regulates human platelet function.

Platelets play a vital role in maintaining haemostasis. Human platelet activation depends on Ca2+ release, leading to cell activation, granule secretion and aggregation. NAADP (nicotinic acid-adenine dinucleotide phosphate) is a Ca2+-releasing second messenger that acts on acidic Ca2+ stores and is...

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Detalles Bibliográficos
Autores principales: Coxon, C, Lewis, A, Sadler, A, Vasudevan, SR, Thomas, A, Dundas, K, Taylor, L, Campbell, R, Gibbins, J, Churchill, G, Tucker, K
Formato: Journal article
Lenguaje:English
Publicado: 2012