Characterization of nuclear structures containing superhelical DNA.

Structures resembling nuclei but depleted of protein may be released by gently lysing cells in solutions containing non-ionic detergents and high concentrations of salt. These nucleoids sediment in gradients containing intercalating agents in a manner characteristic of DNA that is intact, supercoile...

Full description

Bibliographic Details
Main Authors: Cook, P, Brazell, I, Jost, E
Format: Journal article
Language:English
Published: 1976