Structural and interactional studies of the cobalamin-dependent enzyme human methionine synthase
The enzyme methionine synthase (MTR) is a modular five-domain protein that utilises cobalamin (Cbl) as a cofactor to perform a methyl transfer from methyltetrahydrofolate (MeTHF) to homocysteine (Hcy), producing tetrahydrofolate (THF) and methionine (Met). The eventual oxidation of Cbl leads to the...
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| Format: | Thesis |
| Language: | English |
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2024
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